Oncology by Disease Indication

This list represents a selection of tests available at ARUP. For a full test menu, please refer to the ARUP Laboratory Test Directory.


  Bladder Cancer
8100500 Bladder Tumor Associated Antigen, Urine
8209704 Cytology, Urologic
0080281 NMP22®, Urine
8100600 UroVysion™ FISH, Urine
 
  Bone Cancer/Metastasis
0021020 Alkaline Phosphatase Isoenzymes, Serum or Plasma
0020005 Alkaline Phosphatase, Serum or Plasma
0070053 Bone Specific Alkaline Phosphatase, Serum
0070346 Parathyroid Hormone, Intact, Serum or Plasma
0093014 Parathyroid Hormone-Related Peptide (PTHrP), Plasma
0070236 Procollagen Type I Intact N-Terminal Propeptide, Serum
0080385 Vitamin D, 1, 25-Dihydroxy, Serum or Plasma
 
  Breast Cancer
0080392 Cancer Antigen 27.29, Serum
0080464 Cancer Antigen-Breast (CA 15-3), Serum or Plasma
0080080 Carcinoembryonic Antigen, Serum
2002218 HER-2/neu (PATHWAY(4B5) Tissue Assay, Paraffin
0093399 Circulating Tumor Cell Count (CellSearch™), Whole Blood
8209730 Cytology, Breast Ductal Lavage
8209700 Cytology, Breast Nipple Secretion
0095735 DNA Content/Cell Cycle Analysis, Breast (Paraffin)
0049210 Estrogen/Progesterone Receptor Assay, Paraffin
0049390 HER-2 Gene Amplification by Monoplex PCR, Paraffin
0049218 HER-2/neu by FISH (PathVysion™ HER-2), Paraffin
2004672 HER-2/neu Quantitative by ELISA  
0049174 HercepTest® Tissue Assay, Paraffin
0051090 Neuronal Antibodies (Hu, Ri, Yo, Amphiphysin), IgG by Immunoblot, Serum
0050912 Neuronal Nuclear Antibody (ANNA) Titer IgG by IFA, Serum
0049250 p53 Tissue Assay (Paraffin)
 
  Central Nervous System/Neuroendocrine Cancer
0080420 5-Hydroxyindoleacetic Acid (HIAA), Urine
0049360 1p/19q, d(1;19) Deletion by FISH, Tissue
0080216 Catecholamines Fractionated, Plasma
0080469 Chromogranin A, Serum
0070103 C-Peptide, Serum or Plasma
8209703 Cytology, Cerebrospinal Fluid
0070075 Gastrin, Serum
0099165 Glucagon, Plasma
0080422 Homovanillic Acid (HVA), Urine
0070063 Insulin, Fasting, Serum or Plasma
0081226 Neuron Specific Enolase, CSF
0098198 Neuron Specific Enolase, Serum
0051090 Neuronal Antibodies (Hu, Ri, Yo, Amphiphysin), IgG by Immunoblot, Serum
0049235 N-myc by FISH, Tissue
0098192 Somatostatin, Plasma
0080421 Vanillylmandelic Acid (VMA), Urine
0099435 Vasoactive Intestinal Peptide, Plasma
 
  Endocrine/Adrenal Cancer
0070005 17-Hydroxyprogesterone, Serum or Plasma
0080650 17-Ketosteroids, Urine
0070010 Adrenocorticotropic Hormone, Plasma 
2001638 Androstenedione, Serum
2002498 BRAF V600E Mutation Detection by Pyrosequencing
0070006 Calcitonin, Serum or Plasma
  Catecholamines Fractionated Testing 1
0080469 Chromogranin A, Serum 
0070040 Dehydroepiandrosterone Sulfate, Serum or Plasma
0070125 IGF-1 (Insulin-Like Growth Factor I), Serum or Plasma
0050184 Metanephrines, Plasma (Free)
0080436 Metanephrines, Urine
0051390 Multiple Endocrine Neoplasia Type 2 (MEN2), RET Gene Mutations by Sequencing,
Whole Blood
0051492 Multiple Endocrine Neoplasia Type 2B (MEN2B), RET Gene M918T and A883F Mutations, Whole Blood
0070346 Parathyroid Hormone, Intact , Serum or Plasma
0070115 Prolactin, Serum or Plasma 
  Serotonin Testing 1
0081058 Testosterone, Females or Children, Serum or Plasma
0070421 Thyroglobulin, Serum or Plasma
 
  Gastrointestinal Cancer (includes pancreas and liver)
0080420 5-Hydroxyindoleacetic Acid (HIAA), Urine
0080235 5'Nucleotidase, Serum
0021020 Alkaline Phosphatase Isoenzymes, Serum or Plasma
0080428 Alpha Fetoprotein, Plasma or Serum (Tumor Marker)
0081208 Alpha Fetoprotein, Total and L3 Percent, Serum
  APC Mutation Detection 2
0055691 API2-MLT1, t(11;18) Translocation by RT-PCR, Tissue
0070029 Beta-hCG, Serum Quantitative (Tumor Marker)
0051750 BRAF V600E Mutation with Reflex to MLH1 Promoter Methylation, Paraffin
0080461 Cancer Antigen-GI (CA 19-9), Serum or Plasma
0020746 Cancer Antigen-GI (CA 19-9), Body Fluid
0080080 Carcinoembryonic Antigen, Serum
0020742 Carcinoembryonic Antigen, Fluid
0093399 Circulating Tumor Cell Count (CellSearch™), Whole Blood
0070103 C-Peptide, Serum or Plasma
8209709 Cytology, Gastrointestinal
0081312 Des-gamma-carboxy Prothrombin, Serum 
0095140 DNA Content/Cell Cycle Analysis, Colon (Paraffin)
0070075 Gastrin, Serum
2002674 Gastrointestinal Stromal Tumor Mutation
0099165 Glucagon, Plasma
0081326 Hepatocellular Carcinoma Tumor Marker Panel
  Hereditary Pancreatitis (PRSS1)2
0049302 HNPCC/Lynch Syndrome, Microsatellite Instability by IHC
0051740 HNPCC/Lynch Syndrome, Microsatellite Instability by PCR, Paraffin
2001961 HNPCC/Lynch Syndrome, Familial Specific Mutation (inquire)
0051650 HNPCC/Lynch Syndrome (MLH1) Sequencing & Deletion/Duplication, Whole Blood
0051654 HNPCC/Lynch syndrome (MSH2) Sequencing & Deletion/Duplication, Whole Blood
0051656 HNPCC/Lynch Syndrome (MSH6) Sequencing & Deletion/Duplication, Whole Blood
0051737 HNPCC/Lynch Syndrome (PMS2) Sequencing & Deletion/Duplication, Whole Blood
0070063 Insulin, Fasting, Serum or Plasma
0051510 Juvenile Polyposis (SMAD4) Sequencing, Whole Blood
0040248 KRAS Mutation Detection
0098198 Neuron Specific Enolase, Serum 
0099436 Pancreatic Polypeptide, Serum 
0059444 Purkinje Cell Cytoplasmic Antibody by IFA with Reflex to Titer and Immunoblot, Serum 
0098192 Somatostatin, Plasma
0099435 Vasoactive Intestinal Peptide, Plasma 
 
  Gynecologic Cancer
0070029 Beta-hCG, Serum Quantitative (Tumor Marker)
0080462 Cancer Antigen 125, Serum or Plasma
0080080 Carcinoembryonic Antigen, Serum
8100200 Cytology, Pap 1 Slide
8100400 Cytology, SurePath Liquid-Based Pap Test (AutoCyte PREP System)
8100214 Cytology, SurePath Liquid-Based Pap Test (AutoCyte PREP System) with Reflex to Human Papillomavirus (HPV) DNA Probe, High Risk
8100211 Cytology, ThinPrep® Pap Test
8100212 Cytology, ThinPrep® Pap with Reflex to Human Papillomavirus (HPV) DNA Probe, High Risk
0070045 Estradiol, Serum, Adult Premenopausal Female, Serum or Plasma
0065999 Human Papillomavirus (HPV) DNA Probe, High Risk, Cervical Brush (Digene)
0070137 Inhibin A (Dimer), Serum
0070413 Inhibin B, Serum
0051090 Neuronal Antibodies (Hu, Ri, Yo, Amphiphysin), IgG by Immunoblot, Serum
0050912 Neuronal Nuclear Antibody (ANNA) Titer IgG by IFA, Serum
0059444 Purkinje Cell Cytoplasmic Antibody by IFA with Reflex to Titer and Immunoblot, Serum
0081054 Squamous Cell Carcinoma Antigen, Serum
0081058 Testosterone, Females or Children, Serum or Plasma
 
  Head/Neck Cancer
2002498 BRAF Codon 600 Mutation Detection by Pyrosequencing
0070006 Calcitonin, Serum or Plasma
0081344 Cytokeratin 19 Fragment (CYFRA 21-1), Serum
8209710 Cytology, Oral
8209715 Cytology, Vitreous Fluid
2002899 Human Papillomavirus (HPV) High Risk in situ Hybridization, Paraffin
0098198 Neuron Specific Enolase, Serum 
0070346 Parathyroid Hormone, Intact, Serum or Plasma
0081054 Squamous Cell Carcinoma Antigen, Serum
0070421 Thyroglobulin, Serum or Plasma 
 
  Hematological Oncology
0050444 AML1-ETO, t(8;21) Translocation by RT-PCR
0055691 API2-MLT1, t(11;18) Translocation by RT-PCR
  B-Cell and T-Cell Clonality Assessment by PCR1
  B-Cell and T-Cell Comprehensive Clonality Assessment1
0092099 B-Cell CD20 Expression
  B-Cell Clonality Assessment by Restriction Fragment Southern Blot Hybridization1
  B-Cell Clonality Screening Assay by PCR1
  BCL1-JH, t(11;14) Translocation by PCR1
  BCL2-JH, t(14;18) Translocation by PCR1
0040138 BCR-ABL1 Kinase Domain Mutation Analysis 
0055553 BCR-ABL, t(9;22) Translocation Qualitative by RT-PCR
2005010 BCR-ABL1, Qualitative, with Reflex to BCR-ABL1 Quantitative
0050161 Bence Jones Protein, Qualitative Free Kappa and Lambda Light Chains, Urine
0050618 Bence Jones Protein, Quantitative Free Kappa and Lambda Light Chains, Urine
0080053 Beta-2 Microglobulin, Serum or Plasma
2002292 Chromosome Analysis, Bone Marrow
2002295 Chromosome FISH, CLL Panel
2002298 Chromosome FISH, Interphase
2002298 Chromosome FISH, Metaphase
2002290 Chromosome Analysis, Leukemic Blood
2002294 Chromosome FISH, Multiple Myeloma Panel
2002296 Chromosome Analysis, Solid Tumor
0093194 Chronic Lymphocytic Leukemia Follow up Phenotyping by Flow Cytometry
2002063 Cryoglobulin, Qualitative with Reflex to Quantitative IgA, IgG, & IgM, Serum 
0055346 E2A-PBX1, t(1;19) Translocation by RT-PCR
0050227 Erythropietin, Serum or Plasma
2005400 FLT3 Mutation Detection by PCR
0020642 Human T-Lymphotrophic Virus Types I/II Antibodies, Western Blot 
0051164 Human T-Lymphotropic Virus Types I/II Antibodies with Reflex to HTLV I/II Confirmation
0049381 IgH-CCND1, t(11;14) Translocation by FISH
0040227 IgVH Mutation Analysis by Sequencing
  Immunoglobulin Testing 1
  Interleukin Testing 1
0092209 inv(16) for AML(CBFB-MYH11) by RT-PCR +
0051245 JAK2 Gene, V617F Mutation, Qualitative
0040168 JAK2 Gene, V617F Mutation, Quantitation
0055629 Kaposi Sarcoma-Associated Herpesvirus/Human Herpesvirus 8
0055167 Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum
0095244 Leukemia/Lymphoma Phenotyping (Comprehensive, Bone Marrow)
0095243 Leukemia/Lymphoma Phenotyping (Comprehensive, Miscellaneous)
0096299 Leukemia/Lymphoma Phenotyping (Comprehensive, Whole Blood)
0049000 Leukocyte Alkaline Phosphatase
0050368 Lysozyme, Urine
0050446 MLL-AF4, t(4;11) Translocation by RT-PCR
2004360 Natural Killer Cell Panel
  NPM1 Mutation by PCR and Fragment Analysis1
0093014 Parathyroid Hormone-Related Peptide (PTHrP), Whole Blood
2002871 PML-RARα, t(15;17) Translocation by RT-PCR, Quantitative
0050590 Protein Electrophoresis, CSF
2002109 Protein Electrophoresis with Reflex to Immunofixation Electrophoresis Monoclonal Protein Detection, Quantitation and Characterization, IgA, IgG, and IgM, Serum 
0059444 Purkinje Cell Cytoplasmic Antibody by IFA with Reflex to Titer and Immunoblot, Serum 
0055596 T-Cell Clonality Assessment by Restriction Fragment Southern Blot Hybridization, Fluid
0055567 T-Cell Clonality Screening Assay by PCR, Fluid
0056008 TEL-AML1, t(12;21) Translocation by RT-PCR
0020056 Viscosity, Serum 
 
  Lung Cancer
0070010 Adrenocorticotropic Hormone, Plasma 
0080001 Angiotensin Converting Enzyme, Serum
0080462 Cancer Antigen 125, Serum or Plasma
0080080 Carcinoembryonic Antigen, Serum
0021021 Carotenes, Fractionated, Plasma or Serum 
0080469 Chromogranin A, Serum 
0081344 Cytokeratin Fragments (CYFRA 21-1), Serum
8280005 Cytology, Bronchoalveolar Lavage, Malignancy
8209702 Cytology, Pulmonary
0049234 EGFR by FISH
  EGFR Mutation Analysis for Nonsmall-Cell Lung Cancer 2
0098198 Neuron Specific Enolase, Serum
0081284 Soluble Mesothelin Related Peptides (MESOMARK®), Serum
0081054 Squamous Cell Carcinoma Antigen, Serum
 
  Male Reproductive/Urinary Tract Cancer
0080428 Alpha Fetoprotein, Plasma or Serum (Tumor Marker)
0070029 Beta-hCG, Serum Quantitative Tumor Marker
0080080 Carcinoembryonic Antigen, Serum
0093399 Circulating Tumor Cell Count (CellSearch™), Whole Blood
0080469 Chromogranin A, Serum 
0095145 DNA Content/Cell Cycle Analysis, Prostate (Paraffin)
0080206 Prostate Specific Antigen, Free Percentage (Includes Free PSA and Total PSA), Serum or Plasma
0070121 Prostate Specific Antigen, Total, Serum or Plasma
0070234 Prostate Specific Antigen, Total, Medicare Screening, Serum or Plasma
0080264 Prostate Specific Antigen, Total with Reflex to Free PSA (Includes Free Percentage), Serum or Plasma 
0098581 Prostate Specific Antigen, Ultrasensitive, Serum or Plasma
 
  Paraneoplastic Syndrome
0051090 Neuronal Antibodies (Hu, Ri, Yo, Amphiphysin), IgG by Immunoblot, Serum
0051088 Neuronal Nuclear Antibodies (ANNA) IgG, Immunoblot, Serum
0050904 Neuronal Nuclear Antibody (ANNA) IgG by IFA with Reflex to Titer & Immunoblot, Serum 
0050912 Neuronal Nuclear Antibody (ANNA) Titer IgG by IFA, Serum
2006162 Neuronal Nuclear Antibody (Hu) by IFA with Reflex to Titer and Western Blot, CSF
0059444 Purkinje Cell Cytoplasmic Antibody by IFA with Reflex to Titer and Immunoblot, Serum
 
  Pituitary Cancer
0070010 Adrenocorticotropic Hormone, Plasma
0092526 Alpha Subunit of Pituitary Glycoprotein Hormones, Serum
0070055 Follicle Stimulating Hormone, Serum
0070080 Growth Hormone, Serum or Plasma
0070125 IGF-1 (Insulin-Like Growth Factor I)
0070093 Luteinizing Hormone, Serum
0020765 Macroprolactin, Serum or Plasma
0070115 Prolactin, Serum or Plasma
0020724 Prolactin Macroadenoma, Serum or Plasma
0070145 Thyroid Stimulating Hormone, Serum or Plasma
 
  Sarcoma
0049378 CHOP Gene Rearrangement by FISH, Paraffin
0050165 Cytomegalovirus Antibody, IgG, Serum
0051220 Ewing Sarcoma by RT-PCR
0049335 EWSR1 Break Apart Rearrangement by FISH, Paraffin
  FKHR FISH on Formalin Fixed, Paraffin
2002674 Gastrointestinal Stromal Tumor Mutation
0055629 Kaposi Sarcoma-Associated Herpesvirus/Human Herpesvirus 8, Paraffin
0040113 PAX-FKHR Translocation by RT-PCR
0049380 SYT Rearrangement by FISH, Paraffin
0040114 SYT-SSX, t(X;18) Translocations by RT-PCR
 
  Skin Cancer
0055629 Kaposi Sarcoma-Associated Herpesvirus/Human Herpesvirus 8, Paraffin
0020006 Lactate Dehydrogenase, Serum or Plasma
2001766 S-100B Protein, Serum
 
  Therapeutic Drug Management/Pharmacogenetics
  5-Fluorouracil Monitoring2
  5-Fluorouracil Sensitivity Genotyping (DPYD, MTHFR, and TYMS)2
0040138 BCR-ABL1 Kinase Domain Mutation Analysis
  Busulfan pharmacokinetics2
0051103 Cytochrome P450 2C9 by Tag-IT™ (cyclophosphamide, ifosfamide)
0051104 Cytochrome P450 2C19 by Tag-IT™ (cyclophosphamide, ifosfamide)
0051232 Cytochrome P450 2D6 by Tag-IT™ (tamoxifen)
0049390 HER-2 Gene Amplification by Monoplex PCR, Paraffin (trastuzumab)
  HercepTest®1
  KIT (D816V) Mutation by PCR (imatinib)1
0040248 KRAS Mutation Detection (cetuximab, panitumumab), Paraffin
0091084 Mercaptopurine Quantitation, Serum or Plasma
0090311 Methotrexate, Serum or Plasma
0055655 Methylenetetrahydrofolate Reductase (MTHFR) 2 Mutations
2002871 PML-RAR{alpha}, t(15;17) Translocation by RT-PCR, Quantitative
0092066 Thiopurine Methyltransferase, RBC
0051332 UDP glucuronosyltransferase 1A1 (UGT1A1) Genotyping (irinotecan)
0051370 Warfarin Sensitivity (CYP2C9 and VKORC1) 3 Mutations
 
  Various/General
0070027 Arginine Vasopressin Hormone, Plasma
0080469 Chromogranin A, Serum
2002300 Chromosome Analysis, Lymph Node
2002296 Chromosome Analysis, Solid Tumor
0020414 Creatine Kinase Isoenzymes, Serum
0070485 Cyclic AMP, Urine 
0051394 Cytokine Panel 12 by MAFD, Serum or Plasma
8209701 Cytology, Body Cavity Fluid
8209706 Cytology, Fine Needle Aspirate
0095155 DNA Content/Cell Cycle Analysis, Miscellaneous
0049234 EGFR by FISH
0049350 EGFR pharmDx™ Tissue Assay, Paraffin
0049270 Ki-67 Tissue Assay, Paraffin
0080467 Lipid Associated Sialic Acid, Serum 
0050302 Raji Cell Immune Complex Assay, Serum
0051539 Tumor Necrosis Factor—Alpha, Serum or Plasma
   
  1 Multiple tests are available. Please see the ARUP Laboratory Test Directory for specific information.
 



Cytogenetic Oncology Testing by Disease Type

Available Molecular Cytogenetic Testing/Oncology FISH Probes

General Oncology Services

ARUP’s oncology test menu offers a wide variety of testing designed to answer important clinical questions in the areas of risk prediction, diagnosis, prognosis, monitoring, pharmacogenomics, and therapeutic triage of malignancies. The menu is categorized by disease indication and includes tests offered by different techniques based on diagnostic criteria and tumor type.

A large menu of established tumor markers is available, including traditional markers such as CEA, CAGI, and CA 27.29.

Tests utilizing molecular techniques such as FISH, PCR, and IHC are also available to identify many tumor-specific mutations or increased protein expression.

New esoteric tumor markers include vascular endothelial growth factor for detection of oncogenic transformation, alpha fetoprotein L3 percent and DCP for hepatocellular carcinoma, soluble mesothelian-related peptides for malignant mesothelioma, inhibin B for ovarian granulosa cell tumors, and gastrointestinal stromal tumor mutation.

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org