Click on the thumbnail below to download a copy of thePrenatal Screening and Diagnosis algorithm in PDF format.
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| Patient Information | ||
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| Maternal Serum Screening: Choices for Expectant Parents | ![]() |
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| Maternal Serum Triple Screen | ![]() |
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| Triple Estudio del Suero Maternal | ![]() |
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| Maternal Serum Quadruple Screen | ![]() |
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| Cuadruple de Suero Maternal | ![]() |
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| Maternal Serum Screening: The Integrated Test | ![]() |
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| Maternal Serum Screening: First Trimester Screening | ![]() |
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| Prueba de Suero Materno en el Primer Trimestre | ![]() |
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| First-Trimester Screening | ||
| *Sonographer providing NT measurement must be certified by FASTER trial, NTQR (SMFM), or FMF. Please contact genetic counselor prior to sending first sample to ensure acceptability. | ||
| 0081150 | * First Trimester Screen PAPP-A, hCG, and nuchal translucency (NT) measurement | ![]() |
| Combined First- and Second-Trimester Screening | ||
| *Sonographer providing NT measurement must be certified by FASTER trial, NTQR (SMFM), or FMF. Please contact genetic counselor prior to sending first sample to ensure acceptability. | ||
| 0081062 | * Integrated Screen, Specimen #1 PAPP-A, nuchal translucency (NT) measurement; risk result provided after specimen #2. Serum-only integrated testing is available if NT measurement cannot be obtained or if sonographer is not NT certified. |
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| 0081064 | Integrated Screen, Specimen #2 Alpha Fetoprotein, hCG, Estriol, and Inhibin A; combined risk result for specimens #1 and #2 | |
| 0081293 | * Sequential Screen, Specimen #1 PAPP-A, nuchal translucency (NT) measurement Interpretation—Abnormal: Pregnancy is at ≥1 in 25 risk of Down syndrome or ≥ 1 in 100 for Trisomy 18; diagnostic testing and genetic counseling should be offered. Negative: Down syndrome risk does not exceed 1 in 25; Trisomy 18 risk does not exceed 1 in 100; specimen #2 should be drawn. |
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| 0081294 | Sequential Screen, Specimen #2 Alpha Fetoprotein, hCG, Estriol, and Inhibin A; results combined with specimen #1 to provide final risk. | |
| Second-Trimester Screening | ||
| 0080108 | Triple Screen Alpha Fetoprotein, hCG, and Estriol | |
| 0080269 | Quad Screen Alpha Fetoprotein, hCG, Estriol, and Inhibin A | ![]() |
| 0080434 | Alpha Fetoprotein Only AFP only; after first trimester screening or CVS | |
| 0080427 | AFP (Amniotic Fluid) with Reflex to Acetylcholinesterase | |