Reference Interval:
| Test Number
| Components
| Reference Interval
| | 0020096 | Copper, Serum
| | Age
| Male
| Female
| | 0 up to 6 months
| 20-70 µg/dL
| 20-70 µg/dL
| | 7 months-18 years
| 90-190 µg/dL
| 90-190 µg/dL
| | 19 years and older
| 70-140 µg/dL
| 80-155 µg/dL
|
| | 0050160 | Ceruloplasmin
| 6 months-6 years: 18-37 mg/dL
7-17 years: 20-43 mg/dL
18 years and older: 17-54 mg/dL
| | 0020596 | Copper, Serum Free (Direct)
| 0.0-10.0 µg/dL
|
|
| Interpretive Data: |
Free copper (direct) is determined with serum ultrafiltrate. In Wilson disease or other conditions of copper overload, serum ceruloplasmin is usually low and free copper (direct) is usually high. Other tests used to diagnosis Wilson disease include 24-hour urine copper, and hepatic copper. Slit lamp examination for Kayser-Fleischer rings and genetic testing may also be helpful.
|
| Note: |
Elevated results from tubes not certified metal-free may be due to contamination. Elevated levels should be confirmed with a second specimen collected in a metal-free tube.
|
| CPT Code(s): |
82390 Ceruloplasmin; 82525 Copper; 82525 Copper, free (direct)
|
Cross References: |
Copper Panel, Serum, Copper, Free, Free Copper Index, Wilson Disease Screening Test |