ARUP's Laboratory Test Directory

ERBB2 (HER2/neu) Gene Amplification by PCR : 0049390

Mnemonic: HER2 PCR

Methodology: Polymerase Chain Reaction
Performed: Varies
Reported: 7-12 days
Specimen Required: Collect: Tumor tissue.

Specimen Preparation: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Transport tissue block or 5 unstained (3-5 micron thick sections). Protect from excessive heat.

Storage/Transport Temperature: Room temperature or refrigerated. Ship in cooled container during summer months.

Remarks: Include surgical pathology report. Only tissue that is clearly tumor (established by histological criteria) should be tested.

Unacceptable Conditions: Less than 25 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer®).

Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Refer to report.

This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

Refer to Statement B under Testing Information at http://www.aruplab.com.
CPT Code(s): 88381 Microdissection; 83907 Lysis; 83898 x2 Amplification; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
Cross References: ERRB2 (HER-2 Gene Amplification by Monoplex PCR, Paraffin)
 
 

 

 

 
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