Reference Interval:
| Test Number
| Components
| Reference Interval
| | | Thyroglobulin
| Effective August 8, 2011
| Age
| Reference Interval
| | 0-11 years
| 2.9-56 ng/mL
| | 12 years and older
| 1.3-31.8 ng/mL
|
| | 0050105 | Thyroglobulin Antibody
| Effective May 7, 2012
0.0-4.0 IU/mL
| | | Percent Recovery
| 80-120%
|
|
| Interpretive Data: |
DxlThyroglobulin (Tg) is measured by the Beckman Coulter Access Dxl method, which has a lower limit of quantification of 0.1 ng/mL. Tg results less than 0.1 ng/mL are consistent with the absence of thyroglobulin-producing thyroid tissue. Results obtained with different assay methods or kits cannot be used interchangeably. The Tg result, regardless of concentration, should not be interpreted as absolute evidence for the presence or absence of papillary or follicular thyroid cancer and is not recommended for use as a screening procedure to detect the presence of cancer in the general population.
Tg antibodies (Tg Ab) are known to interfere with the measurement of Tg. In patients with positive Tg Ab results (greater than 4.0 IU/mL), a recovery study is performed. A recovery of less than 80 percent in any specimen suggests a Tg Ab interference so the Tg concentration cannot be accurately quantified. A Tg result of greater than or equal to 0.1 ng/mL, in the presence of a positive Tg Ab result, qualitatively indicates that Tg is present in the specimen.
|
| CPT Code(s): |
84432 Thyroglobulin; 86800 Thyroglobulin antibody
|
Cross References: |
Thyroglobulin Tumor Marker (Thyroglobulin, Serum or Plasma), Thyroglobulin, Tumor Marker, Serum (Thyroglobulin, Serum or Plasma) |