Zonisamide : ARUP Lab Tests

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Zonisamide : 0097908

Mnemonic: ZONI

Methodology:	Quantitative Enzyme Multiplied Immunoassay Technique
Performed:	Mon-Fri
Reported:	1-4 days
Specimen Required:	Collect: Plain red. Also acceptable: Lavender (K₂ or K₃EDTA) or pink (K₂ EDTA). Specimen Preparation: Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) Storage/Transport Temperature: Refrigerated Unacceptable Conditions: Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution). Stability (collection to initiation of testing): After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 6 weeks

Reference Interval: Therapeutic range not well established.
Interpretive Data:	The proposed therapeutic range for seizure control is 10-40 µg/mL. Concentrations that exceed 80 µg/mL may contribute to adverse effects. Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function.
CPT Code(s):	80299
Cross References:	Excegran (Zonisamide), Zonegran (Zonisamide)

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