ARUP's Laboratory Test Directory

Acute Myelogenous Leukemia Panel by FISH : 2002384
[ image for: Time Sensitive]
Time Sensitive
[ image for: Patient History For Cytogenetic (Chromosome) Studies]
Patient History For Cytogenetic (Chromosome) Studies


Mnemonic: FISH AML P

Methodology: Fluorescence in situ Hybridization
Performed: Sun-Sat
Reported: 3-10 days
Specimen Required: Collect: Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Whole blood in green (sodium heparin).
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.

Specimen Preparation: Transfer bone marrow to a green (sodium heparin). Transport 3 mL bone marrow (Min: 1 mL) OR 10 mL whole blood (Min: 2 mL).

Storage/Transport Temperature: Room temperature.

Remarks: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. (Refer to appropriate Chromosome Analysis test for order instructions). If FISH only is requested, please include copy of previous cytogenetics report.
If cell pellets or dropped cytogenetics slides are not submitted, a processing fee will apply.
This test must be ordered using Cytogenetic test request form #43099 or through your ARUP interface. Submit the Patient History for Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).

Unacceptable Conditions: Frozen specimens. Clotted or paraffin-embedded specimens.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Probes included: RUNX1T1/RUNX1, MLL, and CBFB. The PML/RARα probe (2002363) is automatically added and performed along with the panel, but, due to the need for a fast turnaround time, it is reported and charged separately.

Refer to Statement A under Testing Information at http://www.aruplab.com.
Note: A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
CPT Code(s): 88271 x3 DNA probe; 88275 x3 Interphase in situ hybridization 100-300; 88291 Interpretation and report - Additional CPT codes modifiers may be required for procedures performed to test for oncologic or inherited disorders.
Cross References: Acute Myeloid Leukemia (Acute Myelogenous Leukemia Panel by FISH), Chromosome Analysis (Acute Myelogenous Leukemia Panel by FISH)
 
 

 

 

 
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