Reference Interval:
By report
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| Interpretive Data: |
This test was developed according to recently published guidelines (Cytometry B Clin Cytom. 2010 Jul; 78 (4):211-30),and includes diagnostic WBC analysis using FLAER, CD14, and CD24 as GPI-linked markers with CD15 and CD33 as lineage-specific markers. The lower limit of detection for this test is 0.1 percent PNH cells and is the most accurate measurement of the PNH clone size used to assist with therapeutic decisions in conventional PNH.
For initial diagnosis of PNH, Paroxysmal Nocturnal Hemoglobinuria Panel, RBC and WBC (ARUP test code 2005006) is available. This panel analyzes both RBCs and WBCs.
For delineation of RBC populations Types II and III when the PNH clone is 1 percent or greater, Paroxysmal Nocturnal Hemoglobinuria, High Sensitivity, RBC (ARUP test code 2004366) is available. This test also detects minor (0.005-0.999 percent) PNH clone populations found in bone marrow failure disorders.
Refer to Statement A under Testing Information at http://www.aruplab.com.
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| CPT Code(s): |
86356 CD14; 86356 CD15; 86356 CD24; 86356 CD33; 86356 FLAER
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Cross References: |
PI-Linked Antigens, Monocytes and Granulocytes (Paroxysmal Nocturnal Hemoglobinuria, WBC) |
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